Annual Penn Neuromuscular Symposium
Myasthenia Gravis · CIDP · GBS · MMN · ALS · SMA · Amyloidosis · Gene Therapy
An expert-led neuromuscular symposium exploring available and novel therapies—from immunomodulation to gene therapy—through practical updates, clinical cases, and multidisciplinary discussion.
From immunomodulation to gene therapy
The symposium explores available and novel therapies for patients with neuromuscular disorders, ranging from immunomodulation to gene therapy.
Expert presentations use clinical cases selected from a neuromuscular clinic setting to highlight the application of new diagnostic methods and treatments.
A central goal is to enhance collaboration and knowledge exchange among neurologists and other healthcare professionals while supporting awareness of evolving clinical trials.
- Review novel treatments for myasthenia gravis, SMA, ALS, CIDP, GBS, and MMN
- Explore new diagnostic and treatment approaches for amyloid neuropathy
- Understand gene therapy advances in hereditary myopathies
- Review inflammatory myopathy antibody testing and emerging therapies
- Strengthen clinical reasoning through challenging case presentations
Key Areas Across the Symposium
Focused updates across immune-mediated, hereditary, motor neuron, and systemic neuromuscular disease.
Immune-Mediated Neuropathy
CIDP, GBS, MMN, vasculitis, and autoimmune treatment strategies.
Neuromuscular Junction
Myasthenia gravis updates, novel therapies, and mechanisms of action.
Motor Neuron Disease
SMA and ALS treatment updates, newly approved therapies, and clinical-trial data.
Hereditary Disease & Gene Therapy
Hereditary myopathies, neuropathies, transthyretin amyloidosis, and gene-therapy advances.
What You Will Learn
Objectives provided in the source content.
Symposium Agenda
Complete lecture sequence from welcome through final questions and wrap-up.
- 8:20 AM – 8:30 AMSessionChafic Karam, MD
Welcome
- 8:30 AM – 9:00 AMSessionLauren Elman, MD
Update on SMA and ALS Treatments
- 9:00 AM – 9:30 AMSessionRami Massie, MD
Novel Therapies in CIDP, GBS and MMN
- 9:30 AM – 9:50 AMSessionRebecca Hsu, MD
Case Presentations
- 10:10 AM – 10:50 AMSessionShawn Bird, MD
Updates in Myasthenia Gravis
- 10:50 AM – 11:10 AMSessionChafic Karam, MD
Serum Neurofilament Light Chain in Patients with Peripheral Neuropathy
- 11:10 AM – 11:30 AMSessionMichelle Kaku, MD
Updates in Diagnosis and Management of Hereditary Transthyretin Amyloidosis
- 11:30 AM – 11:50 AMSessionMichael Baer, MD
Case Presentations
- 12:50 PM – 1:20 PMSessionA. Gordon Smith, MD
Arthur Asbury Endowment Lecture
- 1:20 PM – 1:40 PMSessionPaul T. Mcintosh, MD
Case Presentations
- 1:40 PM – 2:10 PMSessionColin Quinn, MD
Update in Treatment of Hereditary Myopathies
- 2:20 PM – 2:40 PMSessionNaomi Amudala, CRNP RN
Updates in the Management of Vasculitis
- 2:40 PM – 3:00 PMSessionNasheed Hossain, MD
Car-T in Auto-immune Disorders
- 3:00 PM – 3:10 PMSessionCourse Faculty
Questions & Wrap Up
Who Should Participate
Designed to support collaboration across the neuromuscular care team.
Conference Director
Chafic Karam, MD
Conference DirectorProfessor of Clinical Neurology; Chief, Neuromuscular Division; Medical Director, Neuromuscular Fellowship Program; Penn Medicine, Philadelphia, PA.
Distinguished Speakers & Faculty
Faculty span neuromuscular medicine, ALS, EMG, hereditary neuropathy, myopathy, amyloidosis, and autoimmune neuromuscular disease.
Shawn Bird, MD
Professor of Neurology; Medical Director, Electromyography Laboratory at HUP; Penn Medicine
David R. Cornblath, MD
Professor Emeritus, Neurology; Johns Hopkins University School of Medicine
Lauren Elman, MD
Professor of Neurology; Director, MDA Clinic; Director, Penn Comprehensive ALS Center; Penn Medicine
Matthew B. Harms, MD
Associate Professor of Neurology; Columbia University Irving School of Medicine
Rebecca Hsu, MD
Assistant Professor of Clinical Neurology; Penn Medicine
Paul Mcintosh, MD
Assistant Professor of Neurology; Penn Medicine
Steven S. Scherer, MD, PhD
Emeritus Professor of Neurology; Penn Medicine
Marcus V.R. Pinto, MD, MS
Neuromuscular Disease Specialist; Mayo Clinic
Rami Massie, MD
Guest Faculty
Michelle Kaku, MD
Guest Faculty
Michael Baer, MD
Guest Faculty
A. Gordon Smith, MD
Arthur Asbury Endowment Lecturer
Colin Quinn, MD
Guest Faculty
Naomi Amudala, CRNP RN
Guest Faculty
Nasheed Hossain, MD
Guest Faculty
Tyler Crissinger, MD
Neuromuscular Fellow, Penn Medicine
Eduardo Perez, MD
Neuromuscular Fellow, Penn Medicine
Review the latest advances in neuromuscular diagnosis and therapy
Study MG, CIDP, GBS, MMN, ALS, SMA, amyloidosis, hereditary myopathies, vasculitis, CAR-T, gene therapy, and case-based decision-making in one focused symposium.
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